האוניברסיטה העברית בירושלים
the hebrew university of jerusalem
הפקולטה למדעי החקלאות, המזון ואיכות הסביבה
faculty of agricultural, food and
environmental quality sciences
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BitterDB
Humans perceive numerous compounds as bitter.
The bitterness of a compound often provides a hint to its potential toxicity,
and aversion from bitterness helps refrain from consuming poisons.
Well known example is strychnine. Some other bitter compounds,
such as caffeine, while toxic in high dosages, are palatable and is
consumed in large quantities. The amount of bitter compounds is estimated
in thousands. But what are these compounds? How similar or different are
their chemical properties? Do they act on the same or on different receptors?
Is it possible to predict bitterness of a molecule?
To enable investigation into these intriguing questions,
we established
BitterDB, a free and searchable database of bitter compounds.