BitterDB

hTAS2R49 - Taste receptor type 2 member 49 help

Properties help

  • Human
  • chr12:11,148,561-11,150,474 UCSC
  • 3
  • 35,358 (Da)


  • MMSFLHIVFSILVVVAFILGNFANGFIALINFIAWVKRQK ISSADQIIAALAVSRVGLLWVILLHWYSTVLNPTSSNLKV IIFISNAWAVTNHFSIWLATSLSIFYLLKIVNFSRLIFHH LKRKAKSVVLVIVLGSLFFLVCHLVMKHTYINVWTEECEG NVTWKIKLRNAMHLSNLTVAMLANLIPFTLTLISFLLLIY SLCKHLKKMQLHGKGSQDPSTKIHIKALQTVTSFLILLAI YFLCLIISFWNFKMRPKEIVLMLCQAFGIIYPSFHSFILI WGNKTLKQTFLSVLWQVTCWAKGQNQSTP

Known Ligands help

Download SDF file of selected compounds.

3D Homology Model help

Click here to download the model PDB file.

When using this 3D model, please cite us:
Promiscuity and selectivity of bitter molecules and their receptors. Bioorg Med Chem 23 (2015) 4082-4091.
doi: 10.1016/j.bmc.2015.04.025

Protein Diagram help

Receptor snake diagram

When using this 2D protein diagram,please cite us:
Ayana Wiener; Marina Shudler; Anat Levit; Masha Y. Niv. BitterDB: a database of bitter compounds. Nucleic Acids Res 2012, 40(Database issue):D413-419.
Click here to view the paper: BitterDB paper

SNPs Table help

ReceptorLocationBW numberResidueMAFdbSNP
TAS2R49EC1 K79E0.2075rs7135018
TAS2R494.58V141I0.1829rs79420812
TAS2R494.6H143Q0.4231rs12226920
TAS2R49EC2H148N 0.4283rs12226919
TAS2R496.46I236V0.4229rs10845281
TAS2R49EC3 F252S0.4229rs10845280
TAS2R49EC3 R255L0.4231rs10845279

Known Mutations Table help

No mutations were reported yet.

Links and Citations:

P59543
t2r20_human
TAS2R20
ENSG00000255837-TAS2R20

3D Visualizer: NGL: A WebGL Protein Viewer
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579. doi: 10.1093/nar/gkv402