BitterDB

hTAS2R40 - Taste receptor type 2 member 40 help

Properties help

  • Human
  • chr7:142,919,172-142,920,142 UCSC
  • 13
  • 36,812 (Da)


  • MATVNTDATDKDISKFKVTFTLVVSGIECITGILGSGFIT AIYGAEWARGKTLPTGDRIMLMLSFSRLLLQIWMMLENIF SLLFRIVYNQNSVYILFKVITVFLNHSNLWFAAWLKVFYC LRIANFNHPLFFLMKRKIIVLMPWLLRLSVLVSLSFSFPL SRDVFNVYVNSSIPIPSSNSTEKKYFSETNMVNLVFFYNM GIFVPLIMFILAATLLILSLKRHTLHMGSNATGSRDPSMK AHIGAIKATSYFLILYIFNAIALFLSTSNIFDTYSSWNIL CKIIMAAYPAGHSVQLILGNPGLRRAWKRFQHQVPLYLKG QTL

Known Ligands help

3D Homology Model help

Click here to download the model PDB file.

When using this 3D model, please cite us:
Promiscuity and selectivity of bitter molecules and their receptors. Bioorg Med Chem 23 (2015) 4082-4091.
doi: 10.1016/j.bmc.2015.04.025

Protein Diagram help

Receptor snake diagram

When using this 2D protein diagram,please cite us:
Ayana Wiener; Marina Shudler; Anat Levit; Masha Y. Niv. BitterDB: a database of bitter compounds. Nucleic Acids Res 2012, 40(Database issue):D413-419.
Click here to view the paper: BitterDB paper

SNPs Table help

ReceptorLocationBW numberResidueMAFdbSNP
TAS2R40EC2 S187Y0.0819rs10260248

Known Mutations Table help

No mutations were reported yet.

Links and Citations:

P59535
t2r40_human
TAS2R40
ENSG00000221937-TAS2R40

3D Visualizer: NGL: A WebGL Protein Viewer
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579. doi: 10.1093/nar/gkv402