BitterDB

hTAS2R8 - Taste receptor type 2 member 8 help

Properties help

  • Human
  • chr12:10,958,651-10,959,579 UCSC
  • 4
  • 35,877 (Da)


  • MFSPADNIFIILITGEFILGILGNGYIALVNWIDWIKKKK ISTVDYILTNLVIARICLISVMVVNGIVIVLNPDVYTKNK QQIVIFTFWTFANYLNMWITTCLNVFYFLKIASSSHPLFL WLKWKIDMVVHWILLGCFAISLLVSLIAAIVLSCDYRFHA IAKHKRNITEMFHVSKIPYFEPLTLFNLFAIVPFIVSLIS FFLLVRSLWRHTKQIKLYATGSRDPSTEVHVRAIKTMTSF IFFFFLYYISSILMTFSYLMTKYKLAVEFGEIAAILYPLG HSLILIVLNNKLRQTFVRMLTCRKIACMI

Known Ligands help

Download SDF file of selected compounds.

3D Homology Model help

Click here to download the model PDB file.

When using this 3D model, please cite us:
Promiscuity and selectivity of bitter molecules and their receptors. Bioorg Med Chem 23 (2015) 4082-4091.
doi: 10.1016/j.bmc.2015.04.025

Protein Diagram help

Receptor snake diagram

When using this 2D protein diagram,please cite us:
Ayana Wiener; Marina Shudler; Anat Levit; Masha Y. Niv. BitterDB: a database of bitter compounds. Nucleic Acids Res 2012, 40(Database issue):D413-419.
Click here to view the paper: BitterDB paper

SNPs Table help

ReceptorLocationBW numberResidueMAFdbSNP
TAS2R8M308V0.1266rs2537817

Known Mutations Table help

No mutations were reported yet.

Links and Citations:

Q9NYW2
ta2r8_human
TAS2R8
ENSG00000121314-TAS2R8

3D Visualizer: NGL: A WebGL Protein Viewer
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579. doi: 10.1093/nar/gkv402