BitterDB

hTAS2R39 - Human (Homo sapiens) Taste Receptor Type 2 Member 39 help

Links and Citations:

P59534
t2r39_human
TAS2R39
ENSG00000236398-TAS2R39
link

Properties help

  • Human
  • chr7:142,880,512-142,881,527 UCSC
  • 122
  • 38,626 (Da)


  • MLGRCFPPDTKEKQQLRMTKLCDPAESELSPFLITLILAV LLAEYLIGIIANGFIMAIHAAEWVQNKAVSTSGRILVFLS VSRIALQSLMMLEITISSTSLSFYSEDAVYYAFKISFIFL NFCSLWFAAWLSFFYFVKIANFSYPLFLKLRWRITGLIPW LLWLSVFISFSHSMFCINICTVYCNNSFPIHSSNSTKKTY LSEINVVGLAFFFNLGIVTPLIMFILTATLLILSLKRHTL HMGSNATGSNDPSMEAHMGAIKAISYFLILYIFNAVALFI YLSNMFDINSLWNNLCQIIMAAYPASHSILLIQDNPGLRR AWKRLQLRLHLYPKEWTL

Known Ligands help

Please scroll down to see the rest of the ligands.

Download SDF file of selected compounds.

Experimental/ Computational 3D structures help

Here are links to the 3D structures of the receptors. If an experimental structure is available, it is recommended to use the RCSB PDB link. Otherwise, you can use the computationally predicted AlphaFold 3D model.

link

link

Protein Diagram help

Receptor snake diagram

When using this 2D protein diagram,please cite us:
Ayana Wiener; Marina Shudler; Anat Levit; Masha Y. Niv. BitterDB: a database of bitter compounds. Nucleic Acids Res 2012, 40(Database issue):D413-419.
Click here to view the paper: BitterDB paper

SNPs Table help

No SNPs were reported yet.

Known Mutations Table help

ReceptorLocation BW number Residue References
hTAS2R39TM33.32F117doi: 10.1016/bs.mcb.2015.10.005 doi: 10.1371/journal.pone.0118200
hTAS2R39TM33.33I118doi: 10.1016/bs.mcb.2015.10.005 doi: 10.1371/journal.pone.0118200
hTAS2R39TM33.36N121doi: 10.1016/bs.mcb.2015.10.005 doi: 10.1371/journal.pone.0118200
hTAS2R39TM33.37F122doi: 10.1016/bs.mcb.2015.10.005 doi: 10.1371/journal.pone.0118200
hTAS2R39TM33.40L125doi: 10.1016/bs.mcb.2015.10.005 doi: 10.1371/journal.pone.0118200
hTAS2R39TM44.56F170doi: 10.1371/journal.pone.0118200
hTAS2R39TM55.40A210doi: 10.1016/bs.mcb.2015.10.005 doi: 10.1371/journal.pone.0118200
hTAS2R39TM55.41F211doi: 10.1371/journal.pone.0118200
hTAS2R39TM55.44N214doi: 10.1371/journal.pone.0118200
hTAS2R39TM55.45L215doi: 10.1371/journal.pone.0118200
hTAS2R39TM66.48I272doi: 10.1371/journal.pone.0118200
hTAS2R39TM66.51A275doi: 10.1016/bs.mcb.2015.10.005 doi: 10.1371/journal.pone.0118200
hTAS2R39TM66.52V276doi: 10.1016/bs.mcb.2015.10.005 doi: 10.1371/journal.pone.0118200
hTAS2R39TM66.55F279doi: 10.1016/bs.mcb.2015.10.005 doi: 10.1371/journal.pone.0118200
hTAS2R39TM66.56I280doi: 10.1016/bs.mcb.2015.10.005 doi: 10.1371/journal.pone.0118200
hTAS2R39TM77.35N293doi: 10.1016/bs.mcb.2015.10.005 doi: 10.1371/journal.pone.0118200
hTAS2R39TM77.39Q297doi: 10.1016/bs.mcb.2015.10.005 doi: 10.1371/journal.pone.0118200
hTAS2R39TM77.45Y303doi: 10.1371/journal.pone.0118200

Known SNP Table help

ReceptorLocation BW number Residue MAFdbSNP
hTAS2R390.00K197E0.0000rs34169190
hTAS2R390.00S193F0.0000rs35474877