hTAS2R39 - Human (Homo sapiens) Taste Receptor Type 2 Member 39
Alternative Names: Taste receptor type 2 member 57 T2R57
Links and Citations:
Properties
Known Ligands
Please scroll down to see the rest of the ligands.
Quinine
Azathioprine
Chlorpheniramine
Diphenidol
Thiamine
Chloramphenicol
Amarogentin
Chloroquine
Colchicine
Denatonium benzoate
Acetaminophen
Quercetin
Naringenin
L-Histidine
D-phenylalanine,D-Phe,L-phenylalanine,L-Phe
Genistein
Daidzein
(+/-) Equol
Epigallocatechin gallate, egcg,Epigallocatechin gallate,EGCG
Catechin
EC,(+)-Catechin,Epicatechin,(-)-Epicatechin
(-)-Epigallocatechin (EGC),Epigallocatechin,Gallocatechol
(-)-Epicatechin gallate,Ecg,Epicatechin gallate
Genistin
Coumestrol
L-trp,L-tryptophan
LW,Leu-trp
Trp-Trp,WW
Pro-arg,Prolylarginine
Apigenin
Chrysin
5,2'-dihydroxyflavone
5,4'-dihydroxyflavone
6,4'-dihydroxyflavone
7,4-'dihydroxyflavone
5,7'-dimethoxyflavonee
Flavone
Genkwanin
5-hydroxyflavone
4'-hydroxyflavone
4'-hydroxy-7-methoxyflavone
Luteolin
6-methoxyluteolinb
Scutellarein
Tricetin
5,7,2'-trihydroxyflavone
7,3',4'-trihydroxyflavone
Datiscetinb
Fisetin
Gossypetind
Herbacetin
Isorhamnetin
Kaempferol,Kaempherol
Morin
Myricetind
Quercetagetin
3,6,3,4-tetrahydroxyflavone
3,7,4-trihydroxyflavone
Eriodictyolb,Eriodictyol
Hesperetin,Hesperitin
Homoeriodictyolc,Homoeriodictyol
Liquiritigenin
Pinocembrin
Fustin
Silibinind,Silibinin
(+)-taxifolin,taxifoline,taxifolin
Butein
3,2-dihydroxychalcone,3,2'-Dihydroxychalcone
Eriodictyolchalconec,Eriodictyol chalcone
Isoliquiritigenin
2,2,4-trihydroxychalcone
4,2,5-trihydroxychalconee
Phloretinb
Cyanidin chloridec
Pelargoninidin chloride
Acetylgenistin
Biochanin Ag
Formomonetin
Glyciteing
Glyciting,Glycitin
7-hydroxyisoflavoneg
6,7,4-trihydroxyisoflavone
7,8,4-trihydroxyisoflavone
7,3,4-trihydroxyisoflavone
Resveratrol
Sulfuretinc,Sulfuretin
Xanthonee
Denatonium saccharide
Sucralose
Pyrocatechin
Taurocholic acid
2-(1H-indol-3-yl)ethanol
PGG,Pentagalloylglucose (PGG)
Trp-Trp-Trp
LVYPFPGPIHN,Leu-Val-Tyr-Pro-Phe-Pro-Gly-Pro-Ile-His-Asn
YPFPGPIHNS,Tyr-Pro-Phe-Pro-Gly-Pro-Ile-His-Asn-Ser
Iso-Phe,IF,Ile-Phe,Isoleucine-Phenylalanine
Ranitidine
Theaflavin-3'-O-gallate
Theaflavin
pelargoninidin chloride,Pelargonidin chloride
Malonylgenistin
Vitamin B1
Vanillin
Procyanidin B2,Procyanidin B2g (3-O-gallate)
Acetylgenistin
d-Phenylalanine
L-Trp,L-Tryptophan,D-Trp,D-Tryptophan
Cyanidin chloride
Cyanidin chloride
Pelargonidin chloride
Cholate,Cholic acid
Glycocholate
Tenofovir alafenamide
Tenofovir alafenamide fumarate (TAF)
Phe-Phe-Pro-Arg,FFPR
Nirmatrelvir
Amarogentin
Procyanidin B1,Procyanidin B2g,Procyanidin B4
L-Alanine
2,2',4'-trihydroxychalcone
3,2-dihydroxychalcone
Experimental/ Computational 3D structures
Here are links to the 3D structures of the receptors. If an experimental structure is available, it is recommended to use the RCSB PDB link. Otherwise, you can use the computationally predicted AlphaFold 3D model.
RCSB PDB:
link
AlphaFold:
link
Protein Diagram
When using this 2D protein diagram,please cite us:
Ayana Wiener; Marina Shudler; Anat Levit; Masha Y. Niv. BitterDB: a database of bitter compounds. Nucleic Acids Res 2012, 40(Database issue):D413-419.
Click here to view the paper:
BitterDB paper
SNPs Table
No SNPs were reported yet.
Known Mutations Table
Known SNP Table
Receptor Location BW number Residue MAF dbSNP hTAS2R39 0.00 K197E 0.0000 rs34169190
hTAS2R39 0.00 S193F 0.0000 rs35474877