IF, Ile-Phe, Iso-Phe, Isoleucine-Phenylalanine help

BitterDB id=1556
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] URL link
[2] URL link
[3] URL link
[4] Kohl S. et al. Amino Acids and Peptides Activate at Least Five Members of the Human Bitter Taste Receptor Family, Journal of Agricultural and Food Chemistry, 2013, 61 (1), 53-60 PubMed 23214402
[5] Kuhfeld R. F. et al. A comprehensive database of cheese-derived bitter peptides and correlation to their physical properties, Critical Reviews in Food Science and Nutrition, 2023, 1–15 PubMed 37377209
[6] Yu Y. et al. Identification and prediction of milk-derived bitter taste peptides based on peptidomics technology and machine learning method, Food Chemistry, 2024, 433, 137288 PubMed 37683467

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r1 10000.0 PubMed:23214402
Human  hTas2r1 1500.0 7400.0 PubMed:20599705
Human  hTas2r1 10000.0 PubMed:24360415
Human  hTas2r4 10000.0 PubMed:23214402
Human  hTas2r4 10000.0 PubMed:24360415
Human  hTas2r39 10000.0 PubMed:23214402
Human  hTas2r39 10000.0 PubMed:24360415

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 1.479 [mM] Reference

Properties: help

278.3468 [g/mol] 1.69180
1 1
1 1
8

Identifiers: help

C15H22N2O3
WMDZARSFSMZOQO-DRZSPHRISA-N
IF

Links:

[1] 7009596
[2] ZINC000002384816