Nirmatrelvir help

BitterDB id=2586
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Caronia L. et al. Paxlovid mouth likely is mediated by activation of the TAS2R1 bitter receptor by nirmatrelvir, Biochemical and Biophysical Research Communications, 2023, 682, 138-140 PubMed 37806252

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r1 100.0 294.9 PubMed:37806252
Human  hTas2r8 1000.0 PubMed:37806252
Human  hTas2r39 1000.0 PubMed:37806252
Human  hTas2r46 100.0 39.420 PubMed:37806252

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

499.5265 [g/mol] 0.79980
3 5
0 3
11

Identifiers: help

C23H32F3N5O4
LIENCHBZNNMNKG-OJFNHCPVSA-N

Links:

[1] 155903259
[2] ZINC001865086489
[3] 11503