Cholate, Cholic acid 
BitterDB id=2276
Detailed experimental validation described in the associated resource.
References for the compound bitterness
| Resource | Comment | |
|---|---|---|
| [1] | Shu N. et al. Metabolomics identify landscape of food sensory properties, Critical Reviews in Food Science and Nutrition, 2023, 63(27), 8478-8488 PubMed 35435783 | |
| [2] | Ziegler F. et al. Physiological activation of human and mouse bitter taste receptors by bile acids, Communications Biology, 2023, 6, 612 PubMed 37286811 |
Known bitter receptors targets:
| Receptor Name | Effective concentration (μM) | EC50 (μM) | References |
|---|---|---|---|
hTas2r1 |
100.0 | PubMed:37286811 | |
|
hTas2r4 |
30.0 | PubMed:37286811 | |
|
hTas2r14 |
300.0 | PubMed:37286811 | |
|
hTas2r39 |
300.0 | PubMed:37286811 | |
mTas2r105 |
300.0 | PubMed:37286811 | |
|
mTas2r108 |
100.0 | PubMed:37286811 | |
|
mTas2r117 |
10.0 | 20.6 | PubMed:37286811 |
|
mTas2r123 |
10.0 | PubMed:37286811 | |
|
mTas2r126 |
100.0 | PubMed:37286811 | |
|
mTas2r144 |
100.0 | PubMed:37286811 |
Sensory data about the compound bitterness:
| There is no sensory data available |
Properties:
| 408.5714 [g/mol] | 2.88740 |
| 3 | 3 |
| 0 | 4 |
| 4 |
Identifiers:
| C24H40O5 |
|
|
|
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|
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| BHQCQFFYRZLCQQ-OELDTZBJSA-N |
Links:
| [1] | 221493 | ||
| [2] | ZINC000006858022 | ||
| [3] | DB02659 | ||
| [4] | 609 |
