BitterDB ID=875

6-methoxyluteolinb

BitterDB id=875
Detailed experimental validation described in the associated resource.

	Resource	Comment
[1]	Roland WS, van Buren L, Gruppen H, Driesse M, Gouka RJ, et al. (2013). Bitter taste receptor activation by flavonoids and isoflavonoids: modeled structural requirements for activation of hTAS2R14 and hTAS2R39. J Agric Food Chem 61(44): 10454-66. PubMed 24117141
[2]	Roland W. S. U. et al. Bitter Taste Receptor Activation by Flavonoids and Isoflavonoids: Modeled Structural Requirements for Activation of hTAS2R14 and hTAS2R39, J. Agric. Food Chem., 2013, 61, 44, 10454â€“10466 PubMed 24117141
[3]	Li L. et al. A comprehensive review of the metabolism of citrus flavonoids and their binding to bitter taste receptors, Comprehensive Reviews in Food Science and Food Safety, 2023, 22(3), 1763-1793 PubMed 36871162

Receptor Name	Effective concentration (μM)	EC50 (μM)	References
hTas2r14	4.0	11.0	PubMed:24117141
hTas2r14	4.0	11.0	PubMed:36871162
hTas2r39	8.0	22.9	PubMed:24117141
hTas2r39	8.0	22.9	PubMed:36871162

There is no sensory data available

CAS Registry Number: 520-11-6

Formula: C16H12O7

IUPAC Systematic Name:

SMILES:

Canonical SMILES:

InChI Key: FHHSEFRSDKWJKJ-UHFFFAOYSA-N

[1]	PubChem	5317284
[2]	ZINC	ZINC000005998557