Tenofovir alafenamide help

BitterDB id=2285
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Schwiebert E. et al. Inhibition of Bitter Taste from Oral Tenofovir Alafenamide, Molecular Pharmacology, 2021, 99, 5, 319-327 PubMed 33824185

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r1 1000.0 PubMed:33824185
Human  hTas2r8 100.0 PubMed:33824185
Human  hTas2r14 100.0 PubMed:33824185
Human  hTas2r39 1000.0 PubMed:33824185

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

476.4659 [g/mol] 1.39000
2 8
3 3
12

Identifiers: help

C21H29N6O5P
LDEKQSIMHVQZJK-CAQYMETFSA-N

Links:

[1] 9574768
[2] ZINC000100055899
[3] DB09299