Trp-Trp-Trp help

BitterDB id=1254 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] URL link
[2] Kohl S. et al. Amino Acids and Peptides Activate at Least Five Members of the Human Bitter Taste Receptor Family, Journal of Agricultural and Food Chemistry, 2013, 61 (1), 53-60 PubMed 23214402
[3] Cui M. et al. Activation of specific bitter taste receptors by olive oil phenolics and secoiridoids, Sci Rep, 2021, 11, 22340 PubMed 34785711
[4] Yu Y. et al. Identification and prediction of milk-derived bitter taste peptides based on peptidomics technology and machine learning method, Food Chemistry, 2024, 433, 137288 PubMed 37683467
[5] Kohl S, Behrens M, Dunkel A, Hofmann T, Meyerhof W (2013). Amino acids and peptides activate at least five members of the human bitter taste receptor family. J Agric Food Chem 61(1): 53-60. PubMed 23214402

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r1 100.0 PubMed:23214402
Human  hTas2r4 10.0 30.0 PubMed:23214402
Human  hTas2r4 500.0 PubMed:34785711
Human  hTas2r14 100.0 PubMed:23214402
Human  hTas2r39 300.0 PubMed:23214402
Human  hTas2r46 100.0 PubMed:23214402

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

576.6600 [g/mol] 3.53990
7 4
6 6
11

Identifiers: help

C33H32N6O4
KRCAKIVDAFTTGJ-ARVREXMNSA-N
Trp-Trp-Trp

Links:

[1] 44398561