Glycocholate 
BitterDB id=2277
Detailed experimental validation described in the associated resource.
References for the compound bitterness
| Resource | Comment | |
|---|---|---|
| [1] | Ziegler F. et al. Physiological activation of human and mouse bitter taste receptors by bile acids, Communications Biology, 2023, 6, 612 PubMed 37286811 |
Known bitter receptors targets:
| Receptor Name | Effective concentration (μM) | EC50 (μM) | References |
|---|---|---|---|
hTas2r1 |
100.0 | PubMed:37286811 | |
|
hTas2r4 |
30.0 | PubMed:37286811 | |
|
hTas2r14 |
100.0 | PubMed:37286811 | |
|
hTas2r39 |
300.0 | PubMed:37286811 | |
|
hTas2r46 |
1000.0 | PubMed:37286811 | |
mTas2r105 |
300.0 | PubMed:37286811 | |
|
mTas2r108 |
100.0 | PubMed:37286811 | |
|
mTas2r117 |
3.0 | 16.0 | PubMed:37286811 |
|
mTas2r123 |
30.0 | PubMed:37286811 | |
|
mTas2r126 |
100.0 | PubMed:37286811 | |
|
mTas2r144 |
100.0 | PubMed:37286811 |
Sensory data about the compound bitterness:
| There is no sensory data available |
Properties:
| 465.6227 [g/mol] | 1.94720 |
| 4 | 4 |
| 0 | 4 |
| 7 |
Identifiers:
| C26H43NO6 |
|
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| RFDAIACWWDREDC-FRVQLJSFSA-N |
Links:
| [1] | 10140 | ||
| [2] | ZINC000008143774 |
