D-Trp, D-Tryptophan, L-Trp, L-Tryptophan help

BitterDB id=2201
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] URL link
[2] URL link
[3] Kohl S. et al. Amino Acids and Peptides Activate at Least Five Members of the Human Bitter Taste Receptor Family, Journal of Agricultural and Food Chemistry, 2013, 61 (1), 53-60 PubMed 23214402
[4] Delompre T. et al. Taste Perception of Nutrients Found in Nutritional Supplements: A Review, Nutrients, 2019, 11(9), 2050 PubMed 31480669

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r4 10000.0 PubMed:23214402
Human  hTas2r4 10000.0 PubMed:24360415
Human  hTas2r39 21700.0 PubMed:23214402
Human  hTas2r39 21700.0 PubMed:24360415

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

204.2252 [g/mol] 0.62630
1 0
2 2
3

Identifiers: help

C11H12N2O2
QIVBCDIJIAJPQS-SECBINFHSA-N

Links:

[1] 9060
[2] ZINC000000083317