Azathioprine help

BitterDB id=56 , Synthetic
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] Roland W. S. U. et al. Soy Isoflavones and Other Isoflavonoids Activate the Human Bitter Taste Receptors hTAS2R14 and hTAS2R39, Journal of Agricultural and Food Chemistry, 2011, 59 (21), 11764-11771 PubMed 21942422
[3] Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150
[4] Kumar P. Bitter taste receptors of the zebra finch (Taeniopygia guttata), Frontiers in Physiology, 2023, 4, 14, 1233711 PubMed 37860623

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References Sequence variant
Human  hTas2r4 300.0 PubMed:20022913
Human  hTas2r10 300.0 PubMed:20022913
Human  hTas2r14 PubMed:21942422
Human  hTas2r39 1000.0 PubMed:20022913 AAM19321.1
Human  hTas2r46 300.0 PubMed:20022913 AAM19318.1
Chicken  ggTas2r1 300.0 PubMed:25180257
Mouse  mTas2r121 300 PubMed:27226572
Turkey  mgTas2r4 PubMed:37860623

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

277.2700 [g/mol] 1.14580
1 8
3 3
3

Identifiers: help

446-86-6
C9H7N7O2S
LMEKQMALGUDUQG-UHFFFAOYSA-N

Links:

[1] 2265
[2] ZINC000004258316
[3] DB00993
[4] 7120