BitterDB ID=62

Diphenidol help

BitterDB id=62 , Synthetic
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r1 100 PubMed:20022913
Human  hTas2r4 100 PubMed:20022913
Human  hTas2r7 10 PubMed:20022913
Human  hTas2r10 30 PubMed:20022913
Human  hTas2r13 30 PubMed:20022913
Human  hTas2r14 10 PubMed:20022913
Human  hTas2r16 100 PubMed:20022913
Human  hTas2r38 100 PubMed:20022913
Human  hTas2r39 100 PubMed:20022913
Human  hTas2r40 30 PubMed:20022913
Human  hTas2r43 30 PubMed:20022913
Human  hTas2r44 3 PubMed:20022913
Human  hTas2r46 30 PubMed:20022913
Human  hTas2r47 100 PubMed:20022913
Human  hTas2r49 100 PubMed:20022913
Chicken  ggTas2r1 10 PubMed:25180257
Chicken  ggTas2r2 100 PubMed:25180257
Chicken  ggTas2r2 65.7 PubMed:25796330
Chicken  ggTas2r7 100 PubMed:25180257
Mouse  mTas2r105 10 PubMed:27226572
Mouse  mTas2r108 100 PubMed:27226572
Mouse  mTas2r110 100 PubMed:27226572
Mouse  mTas2r123 10 PubMed:27226572
Mouse  mTas2r137 100 PubMed:27226572
Mouse  mTas2r144 100 PubMed:27226572
Cat  fTas2r2 PubMed:26488302
Cat  fTas2r38 PubMed:26488302
Cat  fTas2r46 PubMed:26488302
Cat  fTas2r67 PubMed:26488302

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

309.45 [g/mol] 4.18860
1 2
2 3
6

Identifiers: help

150969-57-6,19-11-4,5336-12-9,722544-51-6,972-02-1
C21H27NO
OGAKLTJNUQRZJU-UHFFFAOYSA-N

Links:

[1] 3055
[2] ZINC000000968266
[3] DB01231
[4] 7163