BitterDB ID=60

Chlorpheniramine help

BitterDB id=60 , Synthetic
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r4 30 PubMed:20022913
Human  hTas2r7 10 PubMed:20022913
Human  hTas2r10 10 PubMed:20022913
Human  hTas2r14 100 PubMed:20022913
Human  hTas2r38 100 PubMed:20022913
Human  hTas2r39 100 PubMed:20022913
Human  hTas2r40 100 PubMed:20022913
Human  hTas2r46 100 PubMed:20022913
Chicken  ggTas2r1 10 PubMed:25180257
Chicken  ggTas2r2 100 PubMed:25180257
Chicken  ggTas2r7 100 PubMed:25180257
Mouse  mTas2r108 100 PubMed:27226572
Mouse  mTas2r140 30 PubMed:27226572
Mouse  mTas2r144 100 PubMed:27226572
Cat  fTas2r2 PubMed:26488302
Cat  fTas2r46 PubMed:26488302

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

274.80 [g/mol] 3.81860
0 2
2 2
5

Identifiers: help

113-92-8,132-22-9,46970-45-0
C16H19ClN2
SOYKEARSMXGVTM-UHFFFAOYSA-N

Links:

[1] 2725
[2] ZINC000000113404 ZINC000000113410
[3] DB01114
[4] 6976