BitterDB

hTAS2R40 - Human (Homo sapiens) Taste Receptor Type 2 Member 40 help

Links and Citations:

P59535
t2r40_human
TAS2R40
ENSG00000221937-TAS2R40
link

Properties help

  • Human
  • chr7:142,919,172-142,920,142 UCSC
  • 19
  • 36,812 (Da)


  • MATVNTDATDKDISKFKVTFTLVVSGIECITGILGSGFIT AIYGAEWARGKTLPTGDRIMLMLSFSRLLLQIWMMLENIF SLLFRIVYNQNSVYILFKVITVFLNHSNLWFAAWLKVFYC LRIANFNHPLFFLMKRKIIVLMPWLLRLSVLVSLSFSFPL SRDVFNVYVNSSIPIPSSNSTEKKYFSETNMVNLVFFYNM GIFVPLIMFILAATLLILSLKRHTLHMGSNATGSRDPSMK AHIGAIKATSYFLILYIFNAIALFLSTSNIFDTYSSWNIL CKIIMAAYPAGHSVQLILGNPGLRRAWKRFQHQVPLYLKG QTL

Known Ligands help

Please scroll down to see the rest of the ligands.

Download SDF file of selected compounds.

Experimental/ Computational 3D structures help

Here are links to the 3D structures of the receptors. If an experimental structure is available, it is recommended to use the RCSB PDB link. Otherwise, you can use the computationally predicted AlphaFold 3D model.

link

link

Protein Diagram help

Receptor snake diagram

When using this 2D protein diagram,please cite us:
Ayana Wiener; Marina Shudler; Anat Levit; Masha Y. Niv. BitterDB: a database of bitter compounds. Nucleic Acids Res 2012, 40(Database issue):D413-419.
Click here to view the paper: BitterDB paper

SNPs Table help

ReceptorLocationBW numberResidueMAFdbSNP
TAS2R40EC2 S187Y0.0819rs10260248

Known Mutations Table help

No mutations were reported yet.

Known SNP Table help

ReceptorLocation BW number Residue MAFdbSNP
hTAS2R40EC2 0.00S187Y0.0819rs10260248
hTAS2R400.00V23L0.0000rs17164164