Xanthohumol help

BitterDB id=76 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Intelmann, D. et al. Three TAS2R Bitter Taste Receptors Mediate the Psychophysical Responses to Bitter Compounds of Hops (Humulus lupulus L.) and Beer. Chemosensory Perception 2, 118-132(2009). springerlink
[2] Yan J. and Tong H. An overview of bitter compounds in foodstuffs: Classifications, evaluation methods for sensory contribution, separation and identification techniques, and mechanism of bitter taste transduction, Comprehensive Reviews in Food Science and Food Safety, 2023, 22(1), PubMed 36382875
[3] Karolkowski A. et al. Non-Volatile Compounds Involved in Bitterness and Astringency of Pulses: A Review, Molecules, 2023, 28(8), 3298 PubMed 37110532

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r1 1 Link
Human  hTas2r1 1.0 PubMed:37110532
Human  hTas2r14 3 Link
Human  hTas2r14 3.0 PubMed:37110532
Human  hTas2r40 3 Link
Human  hTas2r40 3.0 PubMed:37110532
Human  hTas2r47 PubMed:37110532

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 0.01 [mM] Reference
Bitter recognition threshold 0.01 [mM] Reference

Properties: help

354.4000 [g/mol] 4.21680
3 5
2 2
6

Identifiers: help

569-83-5,6754-58-1
C21H22O5
ORXQGKIUCDPEAJ-YRNVUSSQSA-N

Links: