BitterDB id=44 , Natural Detailed experimental validation described in the associated resource.
References for the compound bitterness
Resource
Comment
[1]
Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
Roland W. S. U. et al. Soy Isoflavones and Other Isoflavonoids Activate the Human Bitter Taste Receptors hTAS2R14 and hTAS2R39, Journal of Agricultural and Food Chemistry, 2011, 59 (21), 11764-11771 PubMed 21942422
[6]
Cui M. et al. Activation of specific bitter taste receptors by olive oil phenolics and secoiridoids, Sci Rep, 2021, 11, 22340 PubMed 34785711
[7]
Gibbs M. et al. Bitter taste sensitivity in domestic dogs (Canis familiaris) and its relevance to bitter deterrents of ingestion, PLOS ONE, 2022, 17(11) PubMed 36449493
[8]
Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150
[9]
Fierro F. et al. Inhibiting a promiscuous GPCR: iterative discovery of bitter taste receptor ligands, Cellular and Molecular Life Sciences, 2023, 80, 114 PubMed 37012410
[10]
Yang J. et al. Discovery and verification of bitter components in Panax notoginseng based on the integrated strategy of pharmacophore model, system separation and bitter tracing technology, Food Chemistry, 2023, 428, 136716 PubMed 37413835
hTas2r14
cfTas2r2