Cohumulone help

BitterDB id=73 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Intelmann, D. et al. Three TAS2R Bitter Taste Receptors Mediate the Psychophysical Responses to Bitter Compounds of Hops (Humulus lupulus L.) and Beer. Chemosensory Perception 2, 118-132(2009). springerlink
[2] URL link
[3] Karolkowski A. et al. Non-Volatile Compounds Involved in Bitterness and Astringency of Pulses: A Review, Molecules, 2023, 28(8), 3298 PubMed 37110532
[4] Yang J. et al. Discovery and verification of bitter components in Panax notoginseng based on the integrated strategy of pharmacophore model, system separation and bitter tracing technology, Food Chemistry, 2023, 428, 136716 PubMed 37413835

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r1 0.03 3.3 Link
Human  hTas2r1 0.03 0.2 PubMed:37110532
Human  hTas2r1 0.002083 0.2 Link
Human  hTas2r40 0.003 2.6 Link
Human  hTas2r40 0.003 0.04 PubMed:37110532
Human  hTas2r40 0.003 0.0028 Link
Human  hTas2r47 PubMed:37110532

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 0.017 [mM] Reference
Bitter recognition EC50 >500 [mM] Reference
Bitter recognition threshold 0.017 [mM] Reference

Properties: help

348.4400 [g/mol] 3.86210
3 5
0 1
6

Identifiers: help

142628-20-4
C20H28O5
DRSITEVYZGOOQG-UHFFFAOYSA-N

Links: