BitterDB

hTAS2R49 - Human (Homo sapiens) Taste Receptor Type 2 Member 49 help

Links and Citations:

P59543
t2r20_human
TAS2R20
ENSG00000255837-TAS2R20
link

Properties help

  • Human
  • chr12:11,148,561-11,150,474 UCSC
  • 10
  • 35,358 (Da)


  • MMSFLHIVFSILVVVAFILGNFANGFIALINFIAWVKRQK ISSADQIIAALAVSRVGLLWVILLHWYSTVLNPTSSNLKV IIFISNAWAVTNHFSIWLATSLSIFYLLKIVNFSRLIFHH LKRKAKSVVLVIVLGSLFFLVCHLVMKHTYINVWTEECEG NVTWKIKLRNAMHLSNLTVAMLANLIPFTLTLISFLLLIY SLCKHLKKMQLHGKGSQDPSTKIHIKALQTVTSFLILLAI YFLCLIISFWNFKMRPKEIVLMLCQAFGIIYPSFHSFILI WGNKTLKQTFLSVLWQVTCWAKGQNQSTP

Known Ligands help

Please scroll down to see the rest of the ligands.

Download SDF file of selected compounds.

Experimental/ Computational 3D structures help

Here are links to the 3D structures of the receptors. If an experimental structure is available, it is recommended to use the RCSB PDB link. Otherwise, you can use the computationally predicted AlphaFold 3D model.

link

link

Protein Diagram help

Receptor snake diagram

When using this 2D protein diagram,please cite us:
Ayana Wiener; Marina Shudler; Anat Levit; Masha Y. Niv. BitterDB: a database of bitter compounds. Nucleic Acids Res 2012, 40(Database issue):D413-419.
Click here to view the paper: BitterDB paper

SNPs Table help

ReceptorLocationBW numberResidueMAFdbSNP
TAS2R49EC1 K79E0.2075rs7135018
TAS2R494.58V141I0.1829rs79420812
TAS2R494.6H143Q0.4231rs12226920
TAS2R49EC2H148N 0.4283rs12226919
TAS2R496.46I236V0.4229rs10845281
TAS2R49EC3 F252S0.4229rs10845280
TAS2R49EC3 R255L0.4231rs10845279

Known Mutations Table help

No mutations were reported yet.

Known SNP Table help

ReceptorLocation BW number Residue MAFdbSNP
hTAS2R49EC3 0.00F252S0.4229rs10845280
hTAS2R494.60H143Q0.4231rs12226920
hTAS2R49EC20.00H148N0.4283rs12226919
hTAS2R496.46I236V0.4229rs10845281
hTAS2R49EC1 0.00K79E0.2075rs7135018
hTAS2R49EC3 0.00R255L0.4231rs10845279
hTAS2R494.58V141I0.1829rs79420812