BitterDB

ggTas2r2 - Taste receptor type 2 member 2

Alternative Names: T2R2,gT2R2

Properties

Organism: Chicken
Location: chr1:190,288,727-190,289,720
Number of known ligands: 9
MW: 35,209 (Da)
Sequence:

MLPPVLIVSMCIVAIEVVVGFMGNGFITAVNSINWIKSKR ISAADMILIFLSTSRFILQV TVMMYIHSLYFTDVFKLAS VYKTFGAIWMFVNHASLWFSTWLYVLYCVKIINVTQWLLL Q IKHRITAMIPWLLLGSLLISSVTSFPLLWITPNTYLCR STGNCGDNSTAHISGWDSSHLY LLLLYFTGCFFPLVLSM ITSGLLINSLWKHTKKMQCYVDSFRDPLIDVHLIAIKSII SFL ILYISSFVAQILLTLSTSQSKDFVKVAVSLVVTGAY PSIHSIILIIVNSKLKLALRMLCQ HFMCHLENVNL

Known Ligands

Please scroll down to see the rest of the ligands.

Download SDF file of selected compounds.

	Quinine
	Caffeine
	Coumarin
	Parthenolide
	Chlorpheniramine
	diphenidol
	chloramphenicol
	yohimbine
	Ethylhydrocupreine

3D Homology Model

Click here to download the model PDB file.

When using this 3D model, please cite us:
Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case. Sci Rep 7 (2017) 8223.doi: 10.1038/s41598-017-08344-9

Links and Citations:

UniProt

Q2AB82

3D Visualizer: NGL: A WebGL Protein Viewer
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579. doi: 10.1093/nar/gkv402