BitterDB ID=827

L-trp, L-tryptophan help

BitterDB id=827 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Kohl S, Behrens M, Dunkel A, Hofmann T, Meyerhof W (2013). Amino acids and peptides activate at least five members of the human bitter taste receptor family. J Agric Food Chem 61(1): 53-60. PubMed 23214402
[2] Sonntag T, Kunert C, Dunkel A, Hofmann T (2010). Sensory-guided identification of N-(1-methyl-4-oxoimidazolidin-2-ylidene)-alpha-amino acids as contributors to the thick-sour and mouth-drying orosensation of stewed beef juice. J Agric Food Chem 58(10): 6341-50. PubMed 20420435

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r4 10000 PubMed:23214402

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 5 [mM] Reference

Properties: help

204.23 [g/mol] 1.12230
3 2
2 2

Identifiers: help



[1] 6305
[2] ZINC000000083315
[3] DB00150
[4] 717