BitterDB ID=38

Quinine help

BitterDB id=38 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] PubChem 8549

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r4 10 PubMed:20022913
Human  hTas2r7 10 PubMed:20022913
Human  hTas2r10 10 PubMed:20022913
Human  hTas2r14 10 PubMed:20022913
Human  hTas2r39 10 PubMed:20022913
Human  hTas2r40 10 PubMed:20022913
Human  hTas2r43 10 PubMed:20022913
Human  hTas2r44 10 PubMed:20022913
Human  hTas2r46 10 PubMed:20022913
Chicken  ggTas2r1 10 PubMed:25180257
Chicken  ggTas2r2 10 PubMed:25180257
Chicken  ggTas2r7 10 PubMed:25180257
Mouse  mTas2r105 10 PubMed:27226572
Mouse  mTas2r115 3 PubMed:27226572
Mouse  mTas2r126 10 PubMed:27226572
Mouse  mTas2r137 10 PubMed:27226572
Mouse  mTas2r138 10 PubMed:27226572
Mouse  mTas2r140 3 6 PubMed:27226572
Mouse  mTas2r144 10 PubMed:27226572

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

324.42 [g/mol] 3.17320
1 4
2 5
4

Identifiers: help

130-95-0,13187-99-0,1407-83-6
C20H24N2O2
LOUPRKONTZGTKE-VOMFEXJBSA-N

Links:

[1] 8549
[2] ZINC000003831404 ZINC000006484901
[3] DB00468
[4] 2510