BitterDB

hTAS2R14 - Human (Homo sapiens) Taste Receptor Type 2 Member 14 help

Links and Citations:

Q9NYV8
t2r14_human
TAS2R14
ENSG00000212127-TAS2R14
link

Properties help

  • Human
  • chr12:11,090,854-11,091,806 UCSC
  • 385
  • 36,160 (Da)


  • MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRK ISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEK MFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFL YLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYR RNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLL LIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLY AIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVL ILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS

Known Ligands help

Please scroll down to see the rest of the ligands.

Download SDF file of selected compounds.

Experimental/ Computational 3D structures help

Here are links to the 3D structures of the receptors. If an experimental structure is available, it is recommended to use the RCSB PDB link. Otherwise, you can use the computationally predicted AlphaFold 3D model.

link

link

Protein Diagram help

Receptor snake diagram

When using this 2D protein diagram,please cite us:
Ayana Wiener; Marina Shudler; Anat Levit; Masha Y. Niv. BitterDB: a database of bitter compounds. Nucleic Acids Res 2012, 40(Database issue):D413-419.
Click here to view the paper: BitterDB paper

SNPs Table help

No SNPs were reported yet.

Known Mutations Table help

ReceptorLocation BW number Residue References
hTAS2R14TM22.61W66doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14ECL13.28L85doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14ECL13.29T86doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14ECL13.30N87doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14TM33.32W89doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14TM33.33T90doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14TM33.36N93doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14TM33.37H94doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14ECL25.42T182doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14ECL25.43S183doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14TM55.46F186doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14TM55.47I187doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14TM66.48Y240doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14TM66.49A241doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14TM66.51F243doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14TM66.55F247doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14TM77.36I263doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14TM77.39Q266doi: 10.1016/j.bbagen.2018.07.009
hTAS2R14TM77.42G269doi: 10.1016/j.bbagen.2018.07.009

Known SNP Table help

ReceptorLocation BW number Residue MAFdbSNP
hTAS2R140.00L201F0.0000rs35804287
hTAS2R140.00T86A0.0000rs16925868