Taurolithocholate, Taurolithocholic acid 
BitterDB id=1338
Detailed experimental validation described in the associated resource.
References for the compound bitterness
| Resource | Comment | |
|---|---|---|
| [1] | Behrens M. et al. At the Root of T2R Gene Evolution: Recognition Profiles of Coelacanth and Zebrafish Bitter Receptors, Genome Biology and Evolution, 2021, 13(1) PubMed 33355666 | |
| [2] | Ziegler F. et al. Physiological activation of human and mouse bitter taste receptors by bile acids, Communications Biology, 2023, 6, 612 PubMed 37286811 |
Known bitter receptors targets:
| Receptor Name | Effective concentration (μM) | EC50 (μM) | References |
|---|---|---|---|
hTas2r1 |
0.3 | 1.9 | PubMed:37286811 |
|
hTas2r4 |
1.0 | PubMed:37286811 | |
|
hTas2r14 |
0.3 | PubMed:37286811 | |
|
hTas2r46 |
0.3 | 1.7 | PubMed:37286811 |
mTas2r108 |
1.0 | 2.3 | PubMed:37286811 |
|
mTas2r144 |
3.0 | PubMed:37286811 | |
lchTas2r2 |
300.0 | PubMed:33355666 | |
|
dreTas2r2 |
300.0 | PubMed:33355666 | |
|
dreTas2r4 |
300.0 | PubMed:33355666 |
Sensory data about the compound bitterness:
| There is no sensory data available |
Properties:
| 483.7042 [g/mol] | 4.14180 |
| 2 | 3 |
| 0 | 4 |
| 8 |
Identifiers:
| C26H45NO5S |
|
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| QBYUNVOYXHFVKC-GBURMNQMSA-N |
Links:
| [1] | 439763 | ||
| [2] | ZINC000004095893 |
