BitterDB ID=97

Cucurbitacin E, Cucurbitacins help

BitterDB id=97 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] Glendinning JI (1994). Is the bitter rejection response always adaptive? Physiol Behav 56(6): 1217-27. PubMed 7878094
[3] Merck Index Monograph Number:

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r10 0.01 PubMed:20022913
Mouse  mTas2r105 10 13 PubMed:27226572
Mouse  mTas2r114 30 4.2 PubMed:27226572

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 0.000018 [mM] Reference

Properties: help

556.70 [g/mol] 4.19020
3 8
0 4
5

Identifiers: help

18444-66-1
C32H44O8
NDYMQXYDSVBNLL-OUKQBFOZSA-N

Links:

[1] 5353547