BitterDB ID=976

Tatridin A

BitterDB id=976 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness

	Resource	Comment
[1]	URL link
[2]	Brockhoff A, Behrens M, Massarotti A, Appendino G, Meyerhof W (2007). Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium. J Agric Food Chem 55(15): 6236-43. PubMed 17595105
[3]	Lossow K, Hübner S, Roudnitzky N, Slack JP, Pollastro F, et al. (2016). Comprehensive Analysis of Mouse Bitter Taste Receptors Reveals Different Molecular Receptive Ranges for Orthologous Receptors in Mice and Humans. J Biol Chem 291(29): 15358-77. PubMed 27226572

Known bitter receptors targets:

Receptor Name	Effective concentration (μM)	EC50 (μM)	References
hTas2r10	300.0		PubMed:27226572
hTas2r14	300.0		PubMed:27226572
hTas2r46	30.0		PubMed:17595105
hTas2r46	300.0		PubMed:27226572
mTas2r105	90.0		PubMed:27226572

Sensory data about the compound bitterness:

There is no sensory data available

Properties:

Mol. Weight: 264.3200 [g/mol]	AlogP(octanol-water): 1.49240
# Hydrogen Bond Donor: 2	# Hydrogen Bond Acceptor: 4
# Aromatic Rings: 0	# Rings: 2
# Rotatable Bonds: 0

Identifiers:

Formula: C15H20O4

IUPAC Systematic Name:

SMILES:

Canonical SMILES:

InChI Key: YMNZWKHEJQGPIA-OBQKTHCVSA-N

Links:

[1]

PubChem