BitterDB ID=840

6-Nitrosaccharin

BitterDB id=840
Detailed experimental validation described in the associated resource.

	Resource	Comment
[1]	HAMOR GH (1961). Correlation of chemical structure and taste in the saccharin series. Science 134(3488): 1416-7. PubMed 13904220	a slightlysweet first taste and then an extremelybitter after-taste
[2]	Gibbs M. et al. Bitter taste sensitivity in domestic dogs (Canis familiaris) and its relevance to bitter deterrents of ingestion, PLOS ONE, 2022, 17(11) PubMed 36449493

Receptor Name	Effective concentration (μM)	EC50 (μM)	References
hTas2r38	100		PubMed:15337684
hTas2r44			PubMed:15337684
cfTas2r1	41.0		PubMed:36449493
cfTas2r2	160.0	280.0	PubMed:36449493
cfTas2r4	310.0	1120.0	PubMed:36449493

There is no sensory data available

CAS Registry Number: 22952-24-5,23517-81-9

Formula: C7H4N2O5S

IUPAC Systematic Name:

SMILES:

Canonical SMILES:

InChI Key: HZZFBUZSKAVIOV-UHFFFAOYSA-N

[1]	PubChem	100187
[2]	ZINC	ZINC000004126179