Diphenylthiourea, sulfocarbanilide, sym-Diphenylthiourea, thiocarbanilide help

BitterDB id=63 , Synthetic
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Dotson CD, Zhang L, Xu H, Shin YK, Vigues S, et al. (2008). Bitter taste receptors influence glucose homeostasis. PLoS One 3(12): e3974. PubMed 19092995
[2] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[3] Merck Index Monograph Number:

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r1 PubMed:20022913
Human  hTas2r14 1700 PubMed:20022913
Human  hTas2r14 2.9 PubMed:17253962
Human  hTas2r38 0.3 PubMed:20022913

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

228.32 [g/mol] 3.49550
2 1
2 2
49.9 [mg/kg B.W.]

Identifiers: help



[1] 700999
[2] ZINC000003874019