Cascarillin help

BitterDB id=48 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] URL link
[3] Roland W. S. U. et al. Soy Isoflavones and Other Isoflavonoids Activate the Human Bitter Taste Receptors hTAS2R14 and hTAS2R39, Journal of Agricultural and Food Chemistry, 2011, 59 (21), 11764-11771 PubMed 21942422
[4] Merck Index Monograph Number: 1882 Very bitter taste

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References Sequence variant
Human  hTas2r1 100.0 PubMed:20022913
Human  hTas2r10 100.0 PubMed:20022913
Human  hTas2r14 100.0 PubMed:20022913
Human  hTas2r46 10.0 PubMed:20022913 AAM19318.1
Human  hTas2r47 100.0 PubMed:20022913 AAM19324.1

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

408.4900 [g/mol] 2.38810
3 7
1 3
5

Identifiers: help

10118-56-6
C22H32O7
ZOWKQQIGQBVKSV-BZLLESMPSA-N

Links:

[1] 442011
[2] ZINC000004097881