BitterDB

hTAS2R50 - Taste receptor type 2 member 50 help

Properties help

  • Human
  • chr12:11,138,512-11,139,511 UCSC
  • 2
  • 34,558 (Da)


  • MITFLYIFFSILIMVLFVLGNFANGFIALVNFIDWVKRKK ISSADQILTALAVSRIGLLWALLLNWYLTVLNPAFYSVEL RITSYNAWVVTNHFSMWLAANLSIFYLLKIANFSNLLFLH LKRRVRSVILVILLGTLIFLVCHLLVANMDESMWAEEYEG NMTGKMKLRNTVHLSYLTVTTLWSFIPFTLSLISFLMLIC SLCKHLKKMQLHGEGSQDLSTKVHIKALQTLISFLLLCAI FFLFLIVSVWSPRRLRNDPVVMVSKAVGNIYLAFDSFILI WRTKKLKHTFLLILCQIRC

Known Ligands help

Download SDF file of selected compounds.

3D Homology Model help

Click here to download the model PDB file.

When using this 3D model, please cite us:
Promiscuity and selectivity of bitter molecules and their receptors. Bioorg Med Chem 23 (2015) 4082-4091.
doi: 10.1016/j.bmc.2015.04.025

Protein Diagram help

Receptor snake diagram

When using this 2D protein diagram,please cite us:
Ayana Wiener; Marina Shudler; Anat Levit; Masha Y. Niv. BitterDB: a database of bitter compounds. Nucleic Acids Res 2012, 40(Database issue):D413-419.
Click here to view the paper: BitterDB paper

SNPs Table help

ReceptorLocationBW numberResidueMAFdbSNP
TAS2R505.66C203Y0.4103rs1376251

Known Mutations Table help

No mutations were reported yet.

Links and Citations:

P59544
t2r50_human
TAS2R50
ENSG00000212126-TAS2R50

3D Visualizer: NGL: A WebGL Protein Viewer
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579. doi: 10.1093/nar/gkv402