Progesterone help

BitterDB id=953
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] URL link
[2] Behrens M. et al. At the Root of T2R Gene Evolution: Recognition Profiles of Coelacanth and Zebrafish Bitter Receptors, Genome Biology and Evolution, 2021, 13(1) PubMed 33355666
[3] Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150
[4] Behrens M. et al. A singular shark bitter taste receptor provides insights into the evolution of bitter taste perception, Proceedings of the National Academy of Sciences, 2023, 120(48) PubMed 37956436
[5] Lossow K, Hübner S, Roudnitzky N, Slack JP, Pollastro F, et al. (2016). Comprehensive Analysis of Mouse Bitter Taste Receptors Reveals Different Molecular Receptive Ranges for Orthologous Receptors in Mice and Humans. J Biol Chem 291(29): 15358-77. PubMed 27226572

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r46 3.0 PubMed:27226572
Mouse  mTas2r110 150.0 PubMed:27226572
Mouse  mTas2r114 50.0 2.4 PubMed:27226572
Fish  lchTas2r2 3.0 PubMed:33355666
Shark  scTas2r1 100.0 PubMed:37956436

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

314.4700 [g/mol] 4.72350
0 2
0 4
1

Identifiers: help

257630-50-5,57-83-0
C21H30O2
RJKFOVLPORLFTN-LEKSSAKUSA-N

Links:

[1] 5994
[2] DB00396