7,4-dimethoxyisoflavone help

BitterDB id=914
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Roland WS, van Buren L, Gruppen H, Driesse M, Gouka RJ, et al. (2013). Bitter taste receptor activation by flavonoids and isoflavonoids: modeled structural requirements for activation of hTAS2R14 and hTAS2R39. J Agric Food Chem 61(44): 10454-66. PubMed 24117141
[2] Roland W. S. U. et al. Bitter Taste Receptor Activation by Flavonoids and Isoflavonoids: Modeled Structural Requirements for Activation of hTAS2R14 and hTAS2R39, J. Agric. Food Chem., 2013, 61, 44, 10454–10466 PubMed 24117141
[3] Li L. et al. A comprehensive review of the metabolism of citrus flavonoids and their binding to bitter taste receptors, Comprehensive Reviews in Food Science and Food Safety, 2023, 22(3), 1763-1793 PubMed 36871162

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r14 500.0 PubMed:24117141
Human  hTas2r14 500.0 PubMed:36871162

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

282.3000 [g/mol] 3.47720
0 4
3 3
3

Identifiers: help

1157-39-7
C17H14O4
LPNBCGIVZXHHHO-UHFFFAOYSA-N

Links:

[1] 136419
[2] ZINC000000057588