Leu-Leu-Leu, Leucyl-leucyl-leucine, LLL help

BitterDB id=833
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Kohl S, Behrens M, Dunkel A, Hofmann T, Meyerhof W (2013). Amino acids and peptides activate at least five members of the human bitter taste receptor family. J Agric Food Chem 61(1): 53-60. PubMed 23214402
[2] URL link
[3] URL link
[4] Kohl S. et al. Amino Acids and Peptides Activate at Least Five Members of the Human Bitter Taste Receptor Family, Journal of Agricultural and Food Chemistry, 2013, 61 (1), 53-60 PubMed 23214402
[5] Kuhfeld R. F. et al. A comprehensive database of cheese-derived bitter peptides and correlation to their physical properties, Critical Reviews in Food Science and Nutrition, 2023, 1–15 PubMed 37377209
[6] Yu Y. et al. Identification and prediction of milk-derived bitter taste peptides based on peptidomics technology and machine learning method, Food Chemistry, 2024, 433, 137288 PubMed 37683467

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r4 3000.0 PubMed:23214402
Human  hTas2r4 3000.0 PubMed:24360415

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 1.202 [mM] Reference

Properties: help

357.5000 [g/mol] 1.50620
4 4
0 0
11

Identifiers: help

10329-75-6,110988-78-8
C18H35N3O4
DNDWZFHLZVYOGF-UHFFFAOYSA-N
Leu-Leu-Leu,leucyl-leucyl-leucine

Links: