Phe-trp, Phe-trp phenylalanyltryptophan help

BitterDB id=829
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Kohl S, Behrens M, Dunkel A, Hofmann T, Meyerhof W (2013). Amino acids and peptides activate at least five members of the human bitter taste receptor family. J Agric Food Chem 61(1): 53-60. PubMed 23214402
[2] Kohl S. et al. Amino Acids and Peptides Activate at Least Five Members of the Human Bitter Taste Receptor Family, Journal of Agricultural and Food Chemistry, 2013, 61 (1), 53-60 PubMed 23214402
[3] Yu Y. et al. Identification and prediction of milk-derived bitter taste peptides based on peptidomics technology and machine learning method, Food Chemistry, 2024, 433, 137288 PubMed 37683467

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r1 1000.0 PubMed:23214402
Human  hTas2r4 1000.0 PubMed:23214402

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

351.4100 [g/mol] 1.84980
4 3
3 3
7

Identifiers: help

24587-41-5
C20H21N3O3
JMCOUWKXLXDERB-WMZOPIPTSA-N
Phe-Trp

Links:

[1] 134906
[2] ZINC000002575127