Chlorhexidine help

BitterDB id=59 , Synthetic
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] Roland W. S. U. et al. Soy Isoflavones and Other Isoflavonoids Activate the Human Bitter Taste Receptors hTAS2R14 and hTAS2R39, Journal of Agricultural and Food Chemistry, 2011, 59 (21), 11764-11771 PubMed 21942422
[3] Gibbs M. et al. Bitter taste sensitivity in domestic dogs (Canis familiaris) and its relevance to bitter deterrents of ingestion, PLOS ONE, 2022, 17(11) PubMed 36449493
[4] Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r2 3.0 PubMed:36929150
Human  hTas2r14 0.1 PubMed:20022913
Dog  cfTas2r4 3.7 PubMed:36449493

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

505.4600 [g/mol] 3.33660
6 2
2 2
9

Identifiers: help

337376-15-5,55-56-1
C22H30Cl2N10
GHXZTYHSJHQHIJ-UHFFFAOYSA-N

Links:

[1] 9552079
[2] ZINC000014768621
[3] DB00878