Noscapine help

BitterDB id=52 , Natural
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] URL link
[3] Roland W. S. U. et al. Soy Isoflavones and Other Isoflavonoids Activate the Human Bitter Taste Receptors hTAS2R14 and hTAS2R39, Journal of Agricultural and Food Chemistry, 2011, 59 (21), 11764-11771 PubMed 21942422
[4] Itoigawa A. et al. Functional Diversity and Evolution of Bitter Taste Receptors in Egg-Laying Mammals, Molecular Biology and Evolution, 2022, 39(6) PubMed 35652727

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r14 10.0 PubMed:20022913
Platypus  oaTas2r811 10.0 PubMed:35652727

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

413.4300 [g/mol] 2.88180
0 8
2 5
4
1520 [mg/kg B.W.]

Identifiers: help

128-62-1,1368-39-4,6035-40-1
C22H23NO7
AKNNEGZIBPJZJG-MSOLQXFVSA-N

Links:

[1] 275196
[2] ZINC000019418974