Ritonavir help

BitterDB id=1782
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Chen S. et al. Anti-HIV drugs lopinavir/ritonavir activate bitter taste receptors, Chemical Senses, 2023, 48 PubMed 37625013
[2] URL link

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r1 100.0 78.56 PubMed:37625013
Human  hTas2r8 100.0 49.88 PubMed:37625013
Human  hTas2r13 100.0 9.73 PubMed:37625013
Human  hTas2r14 100.0 30.35 PubMed:37625013

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 0.0702 [mM] Reference
Bitter recognition threshold 0.0702 [mM] Reference

Properties: help

720.9442 [g/mol] 5.66400
4 7
4 4
22

Identifiers: help

C37H48N6O5S2
NCDNCNXCDXHOMX-XGKFQTDJSA-N

Links:

[1] 392622
[2] ZINC000003944422
[3] DB00503
[4] 8804