Saccharin help

BitterDB id=125 , Synthetic
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Rodgers S, Glen RC, Bender A (None). Characterizing bitterness: identification of key structural features and development of a classification model. J Chem Inf Model 46(2): 569-76. PubMed 16562985
[2] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[3] Merck Index Monograph Number:

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r43 280 PubMed:20022913
Human  hTas2r44 140 PubMed:20022913
Human  hTas2r44 170 PubMed:24266887
Mouse  mTas2r105 1000 PubMed:27226572
Mouse  mTas2r109 3000 PubMed:27226572
Mouse  mTas2r135 100 189 PubMed:27226572
Mouse  mTas2r144 10000 PubMed:27226572

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

183.19 [g/mol] 0.11870
1 3
1 2

Identifiers: help



[1] 5143
[2] ZINC000002560357
[3] 5432