BitterDB ID=122

Acesulfame K

BitterDB id=122 , Synthetic
Detailed experimental validation described in the associated resource.

	Resource	Comment
[1]	Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2]	URL link
[3]	Lei W. et al. Functional Analyses of Bitter Taste Receptors in Domestic Cats (Felis catus), PLOS ONE, 2015, 10(10) PubMed 26488302
[4]	Lu Q. et al. Molecular evolution and deorphanization of bitter taste receptors in a vampire bat, Integrative Zoology, 2021, 16(5), 659-669 PubMed 33289344
[5]	Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150

Receptor Name	Effective concentration (μM)	EC50 (μM)	References
hTas2r43	3100.0	10000.0	PubMed:20022913
hTas2r44	250.0	2500.0	PubMed:20022913
mTas2r135	300	380	PubMed:27226572
fcTas2r2	10000.0		PubMed:26488302
droTas2r2	10000.0		PubMed:33289344

There is no sensory data available

CAS Registry Number: 1261988-45-7,55589-62-3

Formula: C4H4KNO4S

IUPAC Systematic Name:

SMILES:

Canonical SMILES:

InChI Key: WBZFUFAFFUEMEI-UHFFFAOYSA-M

[1]	PubChem	23683747
[2]	ZINC	ZINC000002009976