BitterDB ID=117

N-methylthiourea

BitterDB id=117 , Synthetic
Detailed experimental validation described in the associated resource.

	Resource	Comment
[1]	Dotson CD, Zhang L, Xu H, Shin YK, Vigues S, et al. (2008). Bitter taste receptors influence glucose homeostasis. PLoS One 3(12): e3974. PubMed 19092995
[2]	Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[3]	Shimizu T. et al. Expression profiles and functional characterization of common carp (Cyprinus carpio) T2Rs, Biochemistry and Biophysics Reports, 2021, 28, 101123 PubMed 34504956
[4]	Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150

Receptor Name	Effective concentration (μM)	EC50 (μM)	References
hTas2r38	100		PubMed:20022913
ccarpTas2r203-1	300.0		PubMed:34504956

There is no sensory data available

CAS Registry Number: 598-52-7

Formula: C2H6N2S

IUPAC Systematic Name:

SMILES:

Canonical SMILES:

InChI Key: KQJQICVXLJTWQD-UHFFFAOYSA-N

[1]	PubChem	2723704
[2]	ZINC	ZINC000004716359