BitterDB ID=111

Ethylpyrazine

BitterDB id=111 , Natural
Detailed experimental validation described in the associated resource.

	Resource	Comment
[1]	Dotson CD, Zhang L, Xu H, Shin YK, Vigues S, et al. (2008). Bitter taste receptors influence glucose homeostasis. PLoS One 3(12): e3974. PubMed 19092995
[2]	Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[3]	URL link
[4]	Gibbs M. et al. Bitter taste sensitivity in domestic dogs (Canis familiaris) and its relevance to bitter deterrents of ingestion, PLOS ONE, 2022, 17(11) PubMed 36449493
[5]	Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150

Receptor Name	Effective concentration (μM)	EC50 (μM)	References
hTas2r38	300.0	968.0	PubMed:20022913
mTas2r121	3000		PubMed:27226572
mTas2r144	3000		PubMed:27226572
cfTas2r1	11110.0		PubMed:36449493

There is no sensory data available

CAS Registry Number: 1392-50-3,13925-00-3

Formula: C6H8N2

IUPAC Systematic Name:

SMILES:

Canonical SMILES:

InChI Key: KVFIJIWMDBAGDP-UHFFFAOYSA-N

[1]	PubChem	26331
[2]	ZINC	ZINC000004262348