BitterDB ID=956

Sucralose help

BitterDB id=956
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Lossow K, Hbner S, Roudnitzky N, Slack JP, Pollastro F, et al. (2016). Comprehensive Analysis of Mouse Bitter Taste Receptors Reveals Different Molecular Receptive Ranges for Orthologous Receptors in Mice and Humans. J Biol Chem 291(29): 15358-77. PubMed 27226572

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r1 PubMed:27226572
Human  hTas2r4 PubMed:27226572
Human  hTas2r5 PubMed:27226572
Human  hTas2r7 PubMed:27226572
Human  hTas2r8 PubMed:27226572
Human  hTas2r10 PubMed:27226572
Human  hTas2r39 PubMed:27226572
Human  hTas2r41 PubMed:27226572
Human  hTas2r46 PubMed:27226572
Mouse  mTas2r105 PubMed:27226572
Mouse  mTas2r109 PubMed:27226572
Mouse  mTas2r115 PubMed:27226572
Mouse  mTas2r117 4900 PubMed:27226572
Mouse  mTas2r123 PubMed:27226572
Mouse  mTas2r139 PubMed:27226572
Mouse  mTas2r144 PubMed:27226572

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

397.64 [g/mol] -1.65610
5 8
0 2
5

Identifiers: help

56038-13-2
C12H19Cl3O8
BAQAVOSOZGMPRM-QBMZZYIRSA-N

Links:

[1] 71485