Cycloheximid, Cycloheximide help

BitterDB id=98 , Synthetic
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150
[3] Kumar P. Bitter taste receptors of the zebra finch (Taeniopygia guttata), Frontiers in Physiology, 2023, 4, 14, 1233711 PubMed 37860623
[4] Merck Index Monograph Number: 2728

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r10 100 PubMed:20022913
Chicken  ggTas2r7 1000.0 PubMed:25180257
Mouse  mTas2r105 10 0.3 PubMed:27226572
Bird  tgTas2r7 PubMed:37860623

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

281.3500 [g/mol] 1.04150
2 4
0 2
3
2 [mg/kg B.W.]

Identifiers: help

66-81-9
C15H23NO4
YPHMISFOHDHNIV-FSZOTQKASA-N

Links:

[1] 6197
[2] ZINC000003872170
[3] 5433