BitterDB id=937 Detailed experimental validation described in the associated resource.
References for the compound bitterness
Resource
Comment
[1]
Ayenew Z, Puri V, Kumar L, Bansal AK (2009). Trends in pharmaceutical taste masking technologies: a patent review. Recent Pat Drug Deliv Formul 3(1): 26-39. PubMed 19149727
[2]
Levit A, Nowak S, Peters M, Wiener A, Meyerhof W, et al. (2014). The bitter pill: clinical drugs that activate the human bitter taste receptor TAS2R14. FASEB J 28(3): 1181-97. PubMed 24285091
[3]
Levit A. et al. The bitter pill: clinical drugs that activate the human bitter taste receptor TAS2R14, The FASEB Journal, 2014, 28, 1181-1197 PubMed 24285091
[4]
Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150
[5]
Fierro F. et al. Inhibiting a promiscuous GPCR: iterative discovery of bitter taste receptor ligands, Cellular and Molecular Life Sciences, 2023, 80, 114 PubMed 37012410
[6]
Alshehri SM, Park JB, Alsulays BB, Tiwari RV, Almutairy B, et al. (2015). Mefenamic acid taste-masked oral disintegrating tablets with enhanced solubility via molecular interaction produced by hot melt extrusion technology. J Drug Deliv Sci Technol 27: 18-27. PubMed 25914727
hTas2r14