Picrotoxinin 
BitterDB id=89 , Natural
Detailed experimental validation described in the associated resource.
References for the compound bitterness
| Resource | Comment | |
|---|---|---|
| [1] | Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913 | |
| [2] | Merck Index Monograph Number: | Very bitter |
Known bitter receptors targets:
| Receptor Name | Effective concentration (μM) | EC50 (μM) | References |
|---|---|---|---|
hTas2r1 |
1000 | PubMed:20022913 | |
|
hTas2r10 |
1000 | PubMed:20022913 | |
|
hTas2r14 |
3 | PubMed:20022913 | |
|
hTas2r46 |
10 | PubMed:20022913 | |
|
hTas2r46 |
30 | 70 | PubMed:17595105 |
|
hTas2r47 |
1000 | PubMed:20022913 | |
ggTas2r1 |
1000 | PubMed:25180257 | |
|
ggTas2r7 |
300 | PubMed:25180257 | |
mTas2r105 |
300 | 310 | PubMed:27226572 |
|
mTas2r114 |
3000 | PubMed:27226572 |
Sensory data about the compound bitterness:
| There is no sensory data available |
Properties:
| 292.29 [g/mol] | -0.06200 |
| 1 | 6 |
| 0 | 5 |
| 1 |
Identifiers:
| 17617-45-7 |
| C15H16O6 |
|
|
|
|
| PIMZUZSSNYHVCU-YKWPQBAZSA-N |
Links:
| [1] | 442292 | ||
| [2] | ZINC000004098166 | ||
| [3] | 2291 |
