Phe-leu, Phenylalanylleucine help

BitterDB id=836
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Upadhyaya J, Pydi SP, Singh N, Aluko RE, Chelikani P (2010). Bitter taste receptor T2R1 is activated by dipeptides and tripeptides. Biochem Biophys Res Commun 398(2): 331-5. PubMed 20599705 Sensory test threshould is 1.5 mM
[2] Kuhfeld R. F. et al. A comprehensive database of cheese-derived bitter peptides and correlation to their physical properties, Critical Reviews in Food Science and Nutrition, 2023, 1–15 PubMed 37377209
[3] Yu Y. et al. Identification and prediction of milk-derived bitter taste peptides based on peptidomics technology and machine learning method, Food Chemistry, 2024, 433, 137288 PubMed 37683467

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r1 7200 PubMed:20599705

Sensory data about the compound bitterness: help

Sensory Data Type Value Reference
Bitter recognition threshold 15001.413 [mM] Reference

Properties: help

278.3500 [g/mol] 1.17190
3 3
1 1
7

Identifiers: help

3303-55-7
C15H22N2O3
RFCVXVPWSPOMFJ-STQMWFEESA-N
Phe-Leu,phenylalanylleucine

Links:

[1] 76808
[2] ZINC000002390944