BitterDB id=77 , Synthetic Detailed experimental validation described in the associated resource.
References for the compound bitterness
Resource
Comment
[1]
Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2]
Lei W. et al. Functional Analyses of Bitter Taste Receptors in Domestic Cats (Felis catus), PLOS ONE, 2015, 10(10) PubMed 26488302
[3]
Liu K. et al. Plasticity of the ligand binding pocket in the bitter taste receptor T2R7, Biochimica et Biophysica Acta (BBA) - Biomembranes, 2018, 1860, 5, 991-999 PubMed 29355483
[4]
Jaggupilli A. et al. Characterization of the Binding Sites for Bacterial Acyl Homoserine Lactones (AHLs) on Human Bitter Taste Receptors (T2Rs), ACS Infectious Diseases, 2018, 4(7), 1146–1156 PubMed 29799189
[5]
Bhatia V. et al. Extraoral expression and characterization of bitter taste receptors in Astyanax mexicanus (Mexican tetra fish), FASEB BioAdvances, 2022, 4(9), 574-584 PubMed 36089978
[6]
Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150
hTas2r1
ggTas2r1
fcTas2r67
amTas2r1