Haloperidol help

BitterDB id=66 , Synthetic
Detailed experimental validation described in the associated resource.

References for the compound bitterness help

Resource Comment
[1] Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, et al. (2010). The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses 35(2): 157-70. PubMed 20022913
[2] Roland W. S. U. et al. Soy Isoflavones and Other Isoflavonoids Activate the Human Bitter Taste Receptors hTAS2R14 and hTAS2R39, Journal of Agricultural and Food Chemistry, 2011, 59 (21), 11764-11771 PubMed 21942422
[3] Lang T. et al. Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor, Molecular Nutrition & Food Research, 2023, 67(11) PubMed 36929150

Known bitter receptors targets: help

Receptor Name Effective concentration (μM) EC50 (μM) References
Human  hTas2r10 30 PubMed:20022913
Human  hTas2r14 30.0 PubMed:20022913
Mouse  mTas2r110 1 1.2 PubMed:27226572
Mouse  mTas2r144 30 PubMed:27226572

Sensory data about the compound bitterness: help

There is no sensory data available

Properties: help

375.8700 [g/mol] 4.42560
1 3
2 3
6

Identifiers: help

337376-15-5,52-86-8,64461-95-6
C21H23ClFNO2
LNEPOXFFQSENCJ-UHFFFAOYSA-N

Links:

[1] 3559
[2] ZINC000000537822
[3] DB00502
[4] 86